Cantret 50mg Altretamine Capsule

Introduction to Cantret 50mg Altretamine Capsule

What Are The Uses of Cantret 50mg Capsule?

Cantret 50mg Capsule contains Altretamine, an anti-cancer (antineoplastic) medication primarily used in the treatment of:

How Does Cantret 50mg Altretamine Capsule Work?

Cantret 50mg Capsule contains Altretamine, which is classified as an alkylating agent. It works by interfering with the DNA and RNA synthesis in cancer cells. This disruption prevents the cancer cells from dividing and growing, eventually leading to their destruction over time.

Altretamine in Cantret 50mg targets rapidly multiplying cells, like those found in ovarian cancer. By damaging the genetic material within these cells, it reduces tumor size and helps control the progression of the disease. Its selective action makes it valuable in cases where first-line treatments have failed.

Side Effects of Cantret 50mg (Altretamine Capsule)

Cantret 50mg capsules (altretamine) are used in cancer treatment, particularly for epithelial ovarian cancer. Like all medications, Cantret can cause side effects, some of which can be serious. It’s important to note that not all individuals will experience these side effects, and the severity can vary from person to person. Here are some side effects associated with Cantret 50mg capsules:

• Nausea and vomiting
• Swelling in hands, feet, or legs (fluid retention)
• Breast tenderness or enlargement in men (gynecomastia)
• Fatigue or weakness
• Headache
• Increased weight due to fluid buildup

Drug Interactions

Cantret 50mg capsules (altretamine) can interact with other medications and substances, potentially affecting their efficacy or increasing the risk of side effects. It’s crucial for healthcare providers to be aware of these interactions to ensure safe and effective treatment. Here are some important drug interactions associated with Cantret:

• Warfarin and Anticoagulants
• Phenytoin
• Cisplatin and Other Platinum-based Chemotherapy
• Folic Acid Antagonists
• Live Vaccines
• Other Chemotherapy Agents
• Alcohol
• CYP3A4 Inducers and Inhibitors

Manufacturer

Cantret 50mg capsules are manufactured by Natco Pharma. These capsules contain the active ingredient altretamine and are used in the treatment of ovarian cancer.

Storage

Cantret (altretamine) 50mg capsules should be stored according to the manufacturer’s instructions and the guidelines provided by your pharmacist or healthcare provider. Here are typical storage recommendations for medications like Cantret:

• Store Below 25°C (77°F)
• Keep in Original Packaging
• Keep Away from Children and Pets
• Do Not Use Expired Medicine
• Avoid Refrigeration or Freezing

Dosages

Cantret (altretamine) 50mg capsules are typically prescribed for the treatment of ovarian cancer, among other conditions. The dosage of Cantret varies depending on several factors, including the type and severity of cancer, individual patient characteristics, and response to treatment.

For ovarian cancer specifically, a common starting dosage regimen involves administering altretamine at a dose of 260 mg/m²/day, which is usually divided into multiple doses over 14 or 21 days within a 28-day cycle. This means that if a patient’s body surface area (BSA) is known, the dosage can be calculated based on that figure.

Warnings And Precautions

Cantret (altretamine) 50mg capsules, like all medications, come with specific warnings and precautions that patients and healthcare providers should be aware of:

1. Hematologic Effects

• Cantret can cause bone marrow suppression, leading to low blood cell counts (neutropenia, thrombocytopenia). Patients should undergo regular blood tests to monitor these levels during treatment.

2. Neurotoxicity

• Altretamine may cause neurological side effects such as peripheral neuropathy (tingling, numbness in hands and feet), dizziness, and confusion. Patients experiencing these symptoms should notify their healthcare provider promptly.

3. Gastrointestinal Effects

• Nausea, vomiting, and diarrhea are common side effects of Cantret. These symptoms can often be managed with supportive care medications as prescribed by the healthcare provider.

4. Hepatic Impairment

• Cantret can affect liver function, so patients with pre-existing liver conditions or impaired liver function should be closely monitored during treatment.

5. Allergic Reactions

• Patients with a history of hypersensitivity reactions to altretamine or any of its components should not use Cantret.

Frequently Asked Questions

1. How Do I Take Cantret 50mg?

Ans. Cantret capsules are usually taken orally, with specific dosage and schedule determined by your healthcare provider. It’s important to follow their instructions carefully and take the capsules exactly as prescribed.

2. What Should I Do If I Miss A Dose Of Cantret 50mg?

Ans. If you miss a dose of Cantret, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

3. Can I Take Cantret 50 If I Am Pregnant Or Breastfeeding?

Ans. Cantret can cause fetal harm and is not recommended during pregnancy. Effective contraception should be used during treatment. It is not known whether Cantret is excreted in breast milk, so breastfeeding should be avoided during treatment.

4. What Should I Tell My Healthcare Provider Before Starting Cantret 50?

Ans. Before starting Cantret, inform your healthcare provider about any medical conditions you have, especially liver or kidney problems. Also, disclose all medications you are currently taking, including prescription drugs, over-the-counter medicines, and herbal supplements.