What Does Sildenafil Citrate Do? Explained In Detailed

Sildenafil citrate is widely used mainly as a treatment for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). However, most people do not know what does sildenafil citrate do during its mechanism of action.
Sildenafil citrate increases blood flow to the body, especially the penis, making erection easier during sexual stimulation and making erection easier to maintain.
Learning about how it works and what its side effects might be makes it easier to decide on using it. This article provides a clear description of how the drug works, the ways it is used and the most important things to consider.
Table of Contents
Mechanism of Action of Sildenafil Citrate
What does sildenafil citrate do? It works mainly by blocking an enzyme called PDE5 in the body. Usually, these enzymes control blood flow, especially to the penis. When sexually excited, the body produces a substance called cGMP that helps relax and fill the blood vessels of the penis, leading to erection.
However, PDE5 breaks down cGMP and eliminates erections. Sildenafil citrate stops the action of PDE5 and accumulates more cGMP. This will increase blood flow during sexual activity, helping to achieve and maintain erections. Remember that for sildenafil to work, sexual stimulation is required.
How Quickly Does Sildenafil Do Work and How Long Does It Last?
Many users wonder, how quickly does sildenafil citrate do its job? Sildenafil citrate usually begins to work 30 to 60 minutes after people take it. To achieve the optimal effect, it is recommended to take it on an empty stomach.
This is because a fatty diet can slow the absorption and development of sildenafil. The duration of action of sildenafil lasts usually about 4 to 6 hours. However, this duration may vary depending on individual factors such as metabolism, dosage, age, and general health.ย
It is very important to remember that sildenafil does not continue to erect all the time, and during this time, it can be erected in response to sexual stimulation.
Medical Uses of Sildenafil Citrate
1. Erectile Dysfunction
What does Sildenafil Citrate do to treat ED? Sildenafil citrate is used mainly to treat erectile dysfunction (ED). Erectile dysfunction (ED) is a condition in which it is difficult for a man to achieve or maintain an erection that is stiff enough for sex.
This can affect confidence and relationships. Sildenafil citrate works by increasing blood flow to the penis when a man is sexually excited.
Sildenafil Citrate can improve the ability to get and maintain an erection. It is ineffective without sexual stimulation and is not a treatment for ED, but it can improve sexual performance in many men. Before starting treatment with ED, you should consult with your doctor.
2. Pulmonary Arterial Hypertension (PAH)
Sildenafil citrate is used not only to improve erectile dysfunction (ED) but also to treat a disease called Pulmonary Arterial Hypertension (PAH). PAH is a type of high blood pressure that affects the arteries of the lungs and makes it difficult for the heart to pump blood.
Sildenafil citrate works by relaxing the blood vessels of the lungs. This allows blood to flow more easily, which lowers pressure in the lungs and helps the heart work harder. As a result, patients with PAH will be less tired in their daily lives and will be more comfortable breathing.
The Potential Side Effects of Sildenafil Citrate
Although sildenafil citrate is generally well tolerated, it can cause side effects in some people.ย Sildenafil side effects are of varying intensity – from common to serious.
1. Common Side Effects
Common side effects of sildenafil citrate include the following:
- Headache
- Flushing
- Indigestion Disorder
- Nasal Congestion
- Dizziness
- Visual Disturbance
2. Serious Side Effects
Serious side effects of sildenafil citrate, which can be dangerous to your overall health and well-being, include the following:
- Sudden Loss of Vision
- Sudden Hearing Loss
- Chest Pain or Irregular Heartbeat
- Shortness of Breath
- Seizures
- Painful or Prolonged Erection
If any of these serious side effects occur, it is necessary to contact a doctor immediately.
Alternates of Sildenafil Citrate
1. Vidalista 100mg
Vidalista 100mg contains tadalafil, another PDE5 inhibitor used in ED treatment. Tadalafil has a longer duration of action than sildenafil, and the effect lasts up to 36 hours. The longer duration of action enables more spontaneous sexual activity. However, the onset of tadalafil action is slow and may take up to 2 hours to start.
2. Kamagra Tablets
Kamagra Tablets also contain sildenafil citrate and are used to treat ED. It works like other sildenafil drugs and increases blood flow to the penis during sexual stimulation. Kamagra is more affordable than the brand’s sildenafil drugs.
Important Considerations About Sildenafil Citrate
- Dosage: There are different doses of sildenafil citrate, usually ranging from 25 mg to 100 mg. The appropriate dose should be determined by a health professional based on individual needs and health status.
- Alcohol and Food: Drinking alcohol or a high-fat diet before taking sildenafil can affect its effect. Alcohol increases the risk of side effects, and fatty foods may slow the onset of drug effects.
- Interaction: Sildenafil can interact with several drugs, especially nitrates used for chest pain, which leads to potentially dangerous falls in blood pressure. It is essential to report to your health care provider all the drugs and supplements you are taking.
Conclusion
By Knowing what does sildenafil citrate do is key to using it safely and effectively. Sildenafil citrate mainly improves blood flow and helps a man with erectile dysfunction to get erect during sexual activity and maintain it.
It can also relax pulmonary blood vessels and facilitate cardiac activity, helping patients with pulmonary arterial hypertension. Sildenafil citrate is beneficial, but it is important to note possible side effects and drug interactions.
Before taking a drug, be sure to consult a healthcare professional. This Go ED article is for informational purposes only and is not medical advice. Consult your healthcare professional for more information.
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